孕妇沙眼衣原体及解脲支原体感染的相关因素研究

The related study of the infection of UU and CT in pregnant women.

目的前瞻性研究孕妇沙眼衣原体(CT)和解脲支原体(UU)的感染情况,探讨与UU、CT感染相关的危险因素。方法选取门诊行产前检查及住院待产的正常孕妇132例,采用ELISA方法检测母体血清中的抗UUIgG和抗CTIgG抗体。结果(1)孕妇抗UU IgG抗体检出率为17.42%,抗CT IgG抗体检出率为38.63%;不同孕周、不同年龄组、不同文化程度和不同职业的孕妇其血清中UU IgG、CTIgG的阳性检出率无显著性差异;(2)随着孕次的增加,UU IgG的阳性检出率显著增加;(3)自然流产次数与UU IgG的阳性检出率呈正相关;(4)曾患宫颈炎、阴道炎的孕妇CT IgG的阳性检出率明显增加。结论(1)孕妇年龄、不同孕周、不同文化程度与职业不应视为UU、CT感染的危险因素。(2)UU的感染与孕次呈正相关。(3)UU是引起自然流产、CT是引起先兆流产的危险因素。(4)宫颈炎、阴道炎是导致CT感染的一个危险因素。

Objective： Prospectively study the infection rate of UU and CT in pregnant women. To explore the related risk factors of the infections of UU and CT. Methods： Chose normal pregnancy 132 who received antenatal care at clinic or were expecting labor in hospital. ELISA was adopted to detect anti - UU IgG and anti - CT IgG in maternal. Results： （ 1 ） Positive rate of anti - UU IgG is 17. 42% and anti - CT IgG is 38. 63% in pregnant women. No obvious difference of the positive rate of anti - UU IgG or anti - CT IgG was found at different gestation weeks, age, culture degree and career. （2） The positive rate of anti - UU IgG increased significantly with the increase of the times of pregnance. （3） The times of spontaneous abortion correlated positively with the positive rate of anti - UU igG （P 〈0. 05）. （4） The positive rate of anti -CT IgG increased significantly in the pregnant women with chronic cervicitis and vaginitis （P 〈0. 05）. Conclusion： （1） Age, gestation weeks, culture degree and career in pregnant women shouldn＇t be regarded as risk factors. （2） The times of pregnancy correlates positively with the incidence of UU. （3） The infection of UU can result in spontaneous abortion and CT can result in threatened abortion. （4） Chronic cervicitis and vaginitis are risk factors of the infection of CT.