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药源性血糖异常1590例文献分析 被引量:5

Literature Analysis of 1590 Cases of Drug-induce Pathoglycemia
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摘要 目的:探讨药物引起血糖异常的特点及一般规律.方法:检索1994年1月~2005年6月国内医药卫生期刊报道的药源性血糖异常1 590例,并进行统计、分析.结果:引起血糖异常的药物种类主要以激素及其相关用药(17种)、抗微生物药(13种)、中枢神经系统药(8种)为主,其中位居前2位的分别是格列本脲(699例)、极化液(242例);临床表现以血糖降低为多见.结论:临床工作者应重视药物引起血糖异常的现象,在用药时应加强对患者的血糖监测,确保用药安全. OBJECTIVE:To disscuss the general regularity and characteristics of drug- induced pathoglycemia.METHODS: 1 590 cases of drug - induced pathoglycemia reported in internal medical journals published from Jan. 1994 to Jun .2005 were collected and analyzed.RESULTS: The drugs that induced pathoglycemia were included chiefly hormone and relate drugs(17 species), antimicrobial drugs( 13 species) and central nervous system drugs(8 species), glibenclamide was reported mostly(699 cases) and the next was polarized solution(242 cases).The most clinical manifestation was the decrease of blood sugar.CONC- LUSIONS:Clinician should take care of drug- induced pathoglycemia and strengthen the monitor of the level of patient's blood suguar in use the drug, to make sure of the safety of the drug.
出处 《中国药房》 CAS CSCD 北大核心 2006年第11期847-849,共3页 China Pharmacy
关键词 药品不良反应 血糖异常 文献 分析 Adverse drug reaction Pathoglycemia Literature Analysis
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  • 1薛耀明 沈洁.优降糖的临床合理应用与再评价[J].实用糖尿病杂志,1998,2:14-14.
  • 2王晓红 吕彤.重症外源性低血糖昏迷误诊为脑出血2例[J].中国实用内科杂志,1999,19(8):463-463.
  • 3BIELEFELDT K, REIS HE. Hypoglycemea in type 2 diabetic patients[J]. Med Klin, 1990, 85(3):117.
  • 4ASPLUND K, WIHOLM BE, LUNDMAN B. Severe hypoglycamia during teatment with glipizide[J]. Diabet Med. 1990, 8(8): 726.

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