摘要
目的:比较维拉帕米与山莨菪碱治疗肾绞痛的疗效。方法:153例肾绞痛病人随机分为3组。A组54例(男性35例,女性19例;年龄35±s9a)采用维拉帕米20mg;B组48例(男性30例,女性18例;年龄34±7旬采用维拉帕米80mg;C组51例(男性32例,女性19例;年龄37±10a)采用山莨菪碱20mg。以上3个药分别加入5%葡萄糖液250mL,静脉滴注,且于1h滴完。结果:A组总有效率89%,B组92%,C组73%;A,B2组分别与C组比较,差别均有显著意义(P<0.05)。B组显效率明显优于A或C组(P<0.05)。结论:B(维拉帕米80mg)组疗效最佳。
AIM: To compare the efficacy of verapamil in treating renal colic with that of anisodamine. METHODS: 153 patients with renal colic were randomly divided into 3 groups. (A) 54 patients (M 35, F 19; age 35±s 9 a) received verapamil 20 mg+5% glucose 250 mL, iv, drip, for 1 h. (B) 48 patients (M 30, F 18; age 34±7 a) received verapamil 80 mg+ 5% glucose 250 mL, iv, drip, for 1 h. (C) 51 patients (M 32, F 19, age 37±10 a) received anisodamine 20 mg + 5% glucose 250 mL, iv, drip,for 1 h. RESULTS: The total response rates in group A (89%) and group B (92%) were better than that of group C (73%) (P<0.05). The marked response rate in group B was better than that of group A and group C (P<0.05). CONCLUSION: The efficacy of verapmil (80 mg) group was the best.
出处
《新药与临床》
CSCD
北大核心
1996年第2期77-78,共2页
关键词
维拉帕米
山莨菪碱
肾绞痛
疗效
verapamil
anisodamine
urinary calculi
colic
atropine derivatives