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番茄红素对CCl_4致大鼠肝肾抗氧化功能改变的保护作用 被引量:3

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摘要 目的观察四氯化碳(CCl4)对大鼠肝肾抗氧化功能的影响及番茄红素的保护作用。方法大鼠灌胃番茄红素4周后,以CCl4腹腔注射24h后处死,测定血清和肝、肾匀浆的超氧化物歧化酶(SOD)活性、谷胱甘肽过氧化物酶(GSH-Px)活力、丙二醛(MDA)含量、谷胱肝肽(GSH)含量及总抗氧化能力(T-AOC)。结果与CCl4组相比,番茄红素组大鼠血清和肝、肾组织的SOD活性、GSH-Px活力上升,MDA含量降低,GSH含量升高,T-AOC升高(P<0·05)。结论番茄红素可以提高大鼠肝和肾的抗氧化能力。
出处 《卫生研究》 CAS CSCD 北大核心 2006年第3期329-330,共2页 Journal of Hygiene Research
基金 黑龙江省教育厅资助项目(No.10551211)
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