舒血宁注射液治疗脑梗死的疗效

Clinical Observation of Effect of Shuxuening Injection on Cerebral Infarction

目的探讨舒血宁注射液治疗脑梗死的临床疗效。方法将118例脑梗死患者随机分为舒血宁注射液治疗组和复方丹参注射液对照组。比较两组治疗前后的血液流变学实验室指标、神经功能缺损程度评分及疗效。结果治疗组患者治疗前、后血液流变学各指标间差异均有显著性意义,且两组患者治疗后血浆粘滞度、纤维蛋白原含量、红细胞变形指数、红细胞聚集指数间差异均有显著性(P<0.05)。治疗后14天起治疗组神经功能缺损评分较对照组明显减少,21天后差异更显著(P<0.01)。治疗后14天疗效评定,治疗组总有效率为86.2%,对照组总有效率为68.3%,两组患者疗效差异有显著性意义(P<0.05)。结论舒血宁注射液治疗脑梗死疗效显著,且安全可靠,为脑梗死的治疗提供了选择的机会。

Aim To study the clinical effect of Shuxuening injection on senile cerebral infarction. Methods 118 cases of senile cerebral infarction were randomly divided into two groups： 58 cases in treatment group were treated with Shuxuening injection, 60 cases in control grouP were treated with compound Salvia injection. Hemorrheological indexes were checked before and after therapy, the neurological deficit scale and curative effect of the two groups were compared. Results Hemorrhelogical indexes were significantly different in treatment group in using Shuxuening injection before and after therapy. In comparison with control group, hemon＇heological indexes such as plasma viscosity, fibrinogen concentration of plasma, deformation index of red blood cell （RBC） and aggregation index of RBC were significantly different（P〈0.05）. The neurological deficit scale in treatment group were significantly lower than those in control group on the 14 th day after treatment, and more on the 21th day （P〈0.01）. On the 14 th day after treatment , the total effective mte of treatment group and control group was 86. 2% and68. 3%. There is obvious difference in two groups of curative effect （P〈0.05）. Condusions Shuxuening injection is efficient in treating senile celebral infarction just with very slight adverse effects, and provides selectable chance in the treatment of senile cerebral infarction.