沈阳市区部分公务员与专业技术人员的血脂水平

Statistical Analysis of Serum Lipid Classification and Phenotyping of Shenyang Professional Populations

目的 研究沈阳职业人群血脂水平及分类特征。方法 采用近年3919例血脂调查资料（男2134例，女1785例，年龄40～89岁）按我国“血脂异常防治建议”并参考美国“NCEP-ATPⅢ指南”作血脂水平及分类研究。结果 研究人群中50岁以上者只有40％左右总胆固醇及甘油三酯都在合适水平（老年女性28．6％）。总胆固醇大于5．2mmol／L中年男性46．7％，女性34．2％；老年前期男性45．1％，女性53．1％；老年男性51．1％，女性63．0％。总胆固醇大于6．2mmol／L者男性多于10％，老年前期及老年女性分别为18．2％及25．8％。高胆固醇血症比高甘油三酯血症约多2倍（除中年组男性外）。高密度脂蛋白胆固醇降低者男性约15％，女性仅5％左右；高密度脂蛋白胆固醇高水平者女性为31．9％～47．3％，男性只有16．5％～21．9％。结论 沈阳中老年人血脂异常已超过半数。提示患动脉粥样硬化性心血管病的风险增高，防治血脂异常势在必行。

Aim To study the characteristics of hpid level phenotyping of Shenyang professional populations. Method 3919cases （M/F=2 134/1 785, aged 40-89）were enrolled in the study. Lipid levels were elassified aecording to the ＂recommended guidelines for prevention and treatment of dyslipidemia＂ of China （1997）and NCEP ATP Ⅲ（2001 ）of us. Results High prevalence of hpid abnormality was found in Shenyang populations, only 40% had desirable total cholesterol （TC） and triglyeeride （TG） level in the group with age above 50. There are 46.7% of the 40 - 49 aged men and 34.2% 40 - 49 aged women, 45.1% of the 50-59 aged men and 53.1% 50-59 aged women, 51.1% men above 60 and 63.0% women above 60 who have TC levels above 5.2 mmol/L. And more than 10% of the men have TC levels above 6.2 mmol/L. 18.2% of the 50 - 59 aged women and 25.8 % of the women above 60 also have TC levels above 6.2 mmol/L. Hyperhpoproteinemia high TC was about twice more than high TG. Decreased high density hpoprotein cholesterol （HDLC）was found in 15% male subjects, butonly5% infemales. The prevalence of high level HDLC was found in 31.9% - 47.3% of female groups, and16.5%-21.9% in male groups. Conclusion The prevalence of hpid abnormality was more than 50% of the studied subjects above age 50, which means that the atherosclerosis disease risk is high in this population. Lipid modification may be indispensable.