泌尿生殖道解脲支原体和人型支原体的分离培养与药敏检测分析

Isolation,culture and drug sensitivity test of ureaplasma ureaplycium(UU) and mycoplasma hominis(MH) from urogenital tract

目的了解余姚市非淋菌性尿道炎(NGU)患者中解脲支原体、人型支原体的感染和耐药状况,以及感染人群的分布情况。方法采用支原体分离/鉴定/计数/药敏一体化试剂盒,检测支原体的培养阳性率和耐药状况。结果896例患者标本中检出解脲支原体阳性495例、人型支原体阳性23例,女性解脲支原体检出率65.00%,男性检出率46.64%,感染者主要为22￣39岁的中青年人。人型支原体的感染率相对较低,但耐药谱广,解脲支原体的耐药情况目前尚可,但仍需合理选择抗生素。结论非淋菌性尿道炎中,解脲支原体是最常见的致病微生物之一,其检出及药敏试验能为临床合理应用抗生素进行治疗提供有效的指导和支持。

Objective The study was conducted to understand the infection and drug resistance of ureaplasma ureaplycium （UU） and mycoplasma hominis （MH） among patients of nongonococcal urethritis （NGU） in Yuyao City, as well as the distribution of infected people. Methods An integrated kit for isolation, identification, counting and drug resistance test of mycoplasma was used for testing the positive rate of culture and the drug resistance of the mycoplasma. Results Among the 896 specimens of patients, 495 were found positive UU, and 23 were found positive MH. The dectection rate of UU for the female was 65.00%, while for the male was 46.64%. The infected people were mainly young and middle-aged people from 22 to 39 years old. The infection rate of MH was relative low, but with a broad spectrum of drug resistance, and the drug resistance of UU was acceptable, but relevant antibiotics was still to be selected reasonably. Conclusion For nongonococcal urethritis （NGU）, UU is one of the most common pathogenic microorganisms, and the detection and drug sensitivity test of UU may provide effective instruction and support for reasonable clinical application of antibiotics.