摘要
目的探讨高压氧对脊髓损伤后内源性干细胞的诱导修复。方法脊髓半横断后高压氧治疗,进行行为学评分、电镜及免疫组化检查。结果内源性神经干细胞治疗后较对照组增多。结论高压氧使实验动物内源性神经干细胞增殖、分化加强,脊髓损伤后的功能得到改善。
Objective To investigate the effect of hyperbaric oxygen (HBO) on proliferation and differentiation of endogenous neural stem cells after acute spinal cord half cut-off in rats. Methods The differences of proliferation and differentiation of endogenous neural stem cells between injured group and intervention group were compared. Results There were remarkable differences between injured group and intervention group. Conclusion HBO can promote the proliferation and differentiation of the neural stem cells in rats after spine cord injury.
出处
《中国康复理论与实践》
CSCD
2006年第5期369-371,共3页
Chinese Journal of Rehabilitation Theory and Practice
关键词
脊髓损伤
高压氧
内源性神经干细胞
大鼠
spinal cord injuries
hyperbaric oxygen
endogenous neural stem cells
rats