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两例原位心脏移植术后的远期现状 被引量:3

Long term results in the two cases of orthotopic heart transplantation
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摘要 本文报告2例终末期心脏病患者,术前情况危重,经施行同种原位心脏移植术,现已分别存活3年和1年,心功能情况良好,首例已恢复原工作,另1例也准备返回原工作岗位。本文对该2例原位心脏移植病例做了系统回顾,对心脏移植涉及的术前、术中、术后诸多环节做了侧重介绍,尤其在供心保护,免疫抑制剂使用和排斥反应的诊断处置方面做了详细介绍与讨论。 Two recipients of orthotopic heart transplantation have all recovered from their se- rious heart disease and returned to their previous work with good condition for 3 and 1 year respec- tively.This article discusses with emphasis some steps happened before,during and after the operation of heart transplantation,especially the donor heart protection,immunosuppressant ad- ministration,diagnosis and treatment of rejection.
出处 《中华器官移植杂志》 CAS CSCD 1996年第2期53-54,共2页 Chinese Journal of Organ Transplantation
关键词 心脏移植术 手术后 远期疗效 Heart/transplantation Long-term survival
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  • 1王艳芳,王红勤,元新华.免疫抑制剂研究进展[J].中国药师,2005,8(5):372-373. 被引量:9
  • 2Alexander JW, Metze TJ, Mclntosh MJ, et al. The influence of immunomodulatory diest on transplant success and complications [ J ]. Transplantation, 2005,79 (4) :460.
  • 3国家药典委员会编.中国药典临床用药须知(化学药和生物制品卷)[S].2005版.北京:人民卫生出版社,2005:801.
  • 4Sugitani A, Kitada H, Ota M, et al. Revival of effective and safe high - dose mizoribine for the kidney transplantation[J]. Clin Transplant ,2006, 20(5) :590.
  • 5Staatz CE, Tett SE. Clinical pharmacokinetics and pharmacodynamics of mycophenolate in solid organ transplant recipients[ J]. Clin Pharmacokinet ,2007,46( 1 ) : 13.
  • 6Azzariti A, Porcelli L, Gatti G, et al. Synergie antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells[J]. Biochem Pharmacol,2008,75(5) : 1 035.
  • 7Kaplan B, West P, Neeley H, et al. Use of low dose tacrolimus, mycophenolate mofetil and maintenance IL - 2 receptor blockade in an islet transplant recipient [ J ]. Clin Transplant, 2008,22 (2) : 250.
  • 8Wissing KM, Fomegne G, Broeders N, et al. HLA mismatches remain risk factors for acute kidney allograft rejection in patients receiving quadruple immtmosuppression with anti - interleukin - 2 receptor antibodies[J]. Transplantation ,2008,85(3) :411.
  • 9Efalizumab therapy for atopic dermatitis causes marked Harper EG, Simpson EL, Takiguchi RH, et al. increases in circulating effector memory CD4^+ T cells that express cutaneous lymphocyte antigen [ J ]. J Invest Dermatol, 2008, 128 ( 5 ) : 1 173.
  • 10国家药典委员会.中华人民共和国药典·临床用药须知[S].化学药和生物制品卷.2006年版.北京:人民卫生出版社,2006:801.

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