磷脂复合物对大鼠延缓衰老的作用

THE DELAY-SENILE EFFECT OF PHOSPHATIDE COMPOUND FOOD ON RATS

本文报告了磷脂复合物对９月龄ＳＤ大鼠血红细胞ＳＯＤ活力，心肌丙二醛（ＭＤＡ）含量及尾动脉容积脉搏图的影响，试验表明，基础饲料添加１０％磷脂复合物原粉或稀释粉均能使血红细胞ＳＯＤ活力显著增加，（Ｐ＜０．０１，Ｐ＜０．０５）。其中高剂量组心肌丙二醛含量显著降低（Ｐ＜０．０５），且容积脉搏图中降中峡相对深度显著增加（Ｐ＜０．０５）。结果提示，磷脂复合物有增加血红细胞ＳＯＤ活力，降低脂质过氧化和减少尾动脉外周阻力的作用。

he delay-senile effect of phosphatide compound food on nine-monthold Si)rats, the changes of SOD activity of hemocytes and the caudal ar-tery pulse wave and the malrlonyldialdehyde(MDA)content of cardiac mus-cle was investigated. If 10%of phosphatide compound food or its diluentwds added to the basal feed, the SOD activity of hemocytes was highlyincreased, P<0.01 and P<0.05 respectively. With the addition of highdosage of phosphatide compound,the MDA content of cardiac muscle decr一eased significantly (P<0.05), the relative depth of dicrotic notch of cau一dal artery pulse wave graph was found to be increased significantly(P<0.05),Phosphatide compound food could therefore promote the SOD activity anddecrease the lipid peroxidation and the resistance of caudal arteries of senile mice.