摘要
目的:研究不同静脉麻醉药物对阻塞性睡眠呼吸暂停综合征(obstructive sleep apneasyndrome,OSAS)患者气管插管前后血流动力学以及血浆中一氧化氮(NO)和内皮素(ET)的影响。方法:择期OSAS行悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)的患者30例,根据插管前后给予药物的不同分为3组(n=10)。结果:丙泊酚组插管前后血压、心率、NO/ET均无明显改变。结论:小剂量的丙泊酚是OSAS患者插管期的较好选择。
Objective：We studied the effects of the different intravenous anesthetics on the hemodynamics and the plasma levels＇of nitric oxide（NO）and endothelin（ET）in obstructive sleep apnea syndrome（OSAS）patients induced by stress response to tracheal intubation. Methods：30 selected OSAS patients undergoing uvulopalatopharyngoplasty（ UPPP）, were divided into 3 groups （ n = 10 ） ： A group （ N. S group）, B group （etomidate）, C group（propofol）. Results： In propofol group SBP,DBP,HR and NO/ET remained unchanged during intubation. Conclusions：Small dose propofol is the intravenous anesthetic choice for patients with OSAS during intubation.
出处
《内蒙古医学杂志》
2006年第5期395-397,共3页
Inner Mongolia Medical Journal
