摘要
目的:探讨术前应用咪唑安定的合理剂量。方法:ASA I-Ⅱ级椎管内麻醉或神经阻滞麻醉患者30例,随机分为3组。A组:咪唑安定0.05mg/kg;B组咪唑安定0.075mg/kg;C组咪唑安定0.1mg/kg,每组10例,观察各组入室和肌注30min时的镇静程度和呼吸道通畅程度,随访24h遗忘程度。结果:A组所有患者入室评为4分,B、C组入室时已有90%和100%患者有睡意,24h后各组的遗忘率分别是70%、90%和100%。结论:咪唑安定0.05mg/kg是术前用药的合理剂量。
Objective: Look for the best dose of midazolam for preoperative administration. Methods: 30 ASA2-3 patients who received epidural or spinal anesthesia or nerve block were divided equally into three groups and received 0.05mg/kg,0. 075mg/kg;or 0. lmg/kg midazolam respectively. Studied sedation and airway scores of patients in each group when arriving OR and 30min after muscle injection and evaluted amnesia effects 24 hours after operations. Results:All patients in A group were scored 4 when arriving OR,90 % in B and 100 % in C felt drowsy. Amnesia effects appeared in 70% 90% and 100% patients of A,B and C groups respectively. Conclusions: Giving 0.05mg/kg midazolam is a logical dose for preoperative administration.
出处
《内蒙古医学杂志》
2006年第5期400-401,共2页
Inner Mongolia Medical Journal
关键词
咪唑安定
术前用药
剂量
Midazolam
Preoperative administration
Dose