136例早期乳腺癌保乳治疗的临床研究

The Breast-conserving Therapy of Early Breast Cancer

目的：观察早期乳腺癌保乳手术治疗效果.方法：回顾性分析该院乳腺二科2000～2005年0～Ⅱb期女性乳腺癌患者136例行保乳手术的疗效.采用肿瘤局部扩大切除及腋淋巴结清扫,术后辅以化疗、放疗或内分泌治疗.残留腺体缝合或不缝合以保证乳腺外形.结果：保乳术后乳房外形总体满意.皮下积液发生率为7.3%.随访结果局部复发率为0.7%.无远处转移,无死亡病例.其中1例病人因心理因素于保乳术后1年自行在外院行全乳切除.结论：保乳手术具有创伤小,并发症少,外形改变小,疗效满意,生存质量高等优点.

Objective： To investigate the effects of breast - conserving therapy with early breast cancer. Methods： Analyzed effects of One Hundred and Thirty - six patients with stage 0 ～ Ⅱ b in Breast Department Ⅱ of Jinlin Province Cancer Hospital during 2000 ～ 2005, all patients were operated with wide local excision and axillary lymph node dissection. After operation, chemotherapy, radiation therapy or endocrine therapy were done to insure the shape of the breast, the rudimental galactophore were oversewed or not. Results： The patients are pleased with effect of the breast - conserving therapy, 7. 3% of them had hydrops. The follow - up results indicate that 0.7% of patients suffered from breast tumor relapse, There were on cases of distant relapse and death. Only one patient was excised the whole breast in other hospital one year later because of anxiety. Conclusion： The results of breast - conserving therapy are satisfactory for stage 0 ～Ⅱ b primary breast cancer. It has many excellence, such as little hurt, less syndrome and better effects.