糖尿病肾病病变程度影响因素及预测

Infective factors of diabetic nephropathy class and its forecast

目的研究糖尿病肾病病变程度的影响因素。方法用有序回归分析方法,采用SPSS 12.0统计软件进行统计分析。结果糖尿病肾病的病变程度与尿微量白蛋白、血肌酐有关。在控制其他影响因素的前提下,尿微量白蛋白每提高1μg/min,则糖尿病病变程度上升1个或1个以上病期的可能性增加2.43%;在控制尿微量白蛋白的前提下,血肌酐每提高1μmol/L,则糖尿病病变程度也上升1个或1个以上病期的可能性增加2.22%。结论有序回归分析不仅可以找出糖尿病肾病的影响因素,而且可以定量分析,并进行个案预测。

Objective To study the infective factors of the diabetic nephropathy class. Methods The application of SPSS12.0 statistics software with the method of ordinal regression. Results The degree of diabetic nephropathy was related to urinary microalbumine （Alb） and blood creatinine. When the Alb increased an unit without other influences, the probability of the degree of the diabetic nephropathy to increase one rank or more was 2.43% ; meanwhile, when the blood creatinine increase one unit without the effect of the Alb, the probability of the degree of the diabetic nephropathy to increase one rank or more was 2.22 %. Conclusion Ordinal regression can not only show the infective factors of the diabetic nephropathy, but also can make quantitative analysis as well as individual prognostication.