可降解淀粉微球的性能研究

Study on the Preparation and Properties of Degradable Starch Microspheres

以可溶性淀粉为原料,反相乳液聚合法合成可降解淀粉微球,并测定了它的粒度分布、红外光谱、降解性、载药性等.结果表明：可降解淀粉微球的平均粒径为15.423μm,94%分布在1～50 μm,8 h后被淀粉酶降解11.72%～24.58%,淀粉微球具有很好的可降解性.

Soluble starch was used as raw materials. Degradable starch microspheres（DSMs） were synthesized by the way of reversed-phase emulsion polymerization. Particle size distribution, IR spectrum and degradability of skeleton were investigated. The result showed., mean diameter of synthesized DSMs was 15. 423 μm. 94% of the microspheres were distributed at a range of between 1～50 μm and 11.72 %～24. 58 % were degraded by starch enzyme after 8 h. Synthesized DSMs by the way of reversed-phase emulsion polymerization had good degradability.