失语症恢复的研究与进展(英文)

Research and development of aphasia recovery

目的:临床中约有70%的脑卒中患者存在着不同程度的功能障碍,其中失语症影响了患者的社会交往能力,甚至给社会和家庭带来沉重的经济负担。本文综述了有关失语症恢复机制的文献,力求为进一步的研究提供借鉴。资料来源:应用计算机检索Medline1980-01/2004-01期间的相关文章,检索词“aphasia,recovery”,“language,recovery”,并限定文章语言种类为English。资料选择:对资料进行初审,选取有关失语症恢复机制的相关文献,然后筛除明显不随机临床试验的研究,对剩余的文献查找全文,进一步判断是否为随机对照实验。纳入标准为随机对照临床研究,无论是否为盲法。资料提炼:共收集到22篇关于失语症恢复机制的相关文献,12篇符合纳入标准。排除的10篇试验均为重复的同一研究。资料综合:语言功能的恢复与性别、年龄、受教育程度、病变性质、病变范围、发病到语言康复的时间及患者语言障碍的自知力、自我纠正能力等因素有关,因此,以往的有关失语症恢复机制的研究各有不同的发现和观点。结论:关于失语症的恢复机制,目前尚无统一的结论。脑语言功能的可塑性可能为失语症的恢复机制。

OBJECTIVE： About 70% patients with stroke have dysfunction at various degrees in clinic, especially aphasia would affect their social communication and even offer a serious economic load for family and social. This paper aims to summarize the relevant articles on aphasia recovery so as to provide researching evidences in the future. DATA SOURCES： Relevant articles were retrieved from the Medline with the key words of ＂aphasia, recovery, language, recovery＂ in English from January 1980 to January 2004. STUDY SELECTION： All articles were selected firstly, those which were related to aphasia recovery were selected, and the non-randomly clinical papers were excluded. The full text of rest was looked up to determine whether they were randomized controlled studies or not. Randomized controlled researches were regarded as inclusion criteria regardless of blind way. DATA EXTRACTION： Among 22 articles on aphasia recovery, 12 were selected according to inclusion criteria and 10 were excluded because of duplicated papers.DATA SYNTHESIS： Recovery of language function was related to sex,age, ducational degrees, characteristics of lesion, range of lesion, duration from episode to language recovery, insight and self redress of language disorder. Therefore, there were various findings and views for previous re searches on mechanism of aphasia recovery. CONCLUSION： There is not uniform conclusion on mechanism of aphasia recovery. Compliance of language function in brain may be a mechanism of aphasia recovery.