超声波辐射下区域选择性合成单齿席夫碱

An Efficient Method for Regio-selective Synthesis of Mono-Schiff Base under Ultrasound Irradiation

报道了在非极性溶剂如四氯化碳中，乙二胺与芳香醛在超声波辐射下高产率（92％～96％）区域选择性合成单齿席夫碱RCH=NCH2CH2NH2，并用NMR，MS，IR和元素分析对其结构进行表征,1HNMR和IR研究发现单齿席夫碱2a—d在乙醇溶液中重结晶或加热到50℃以上可转变为双齿席夫碱la—d。

Mono-Schiff base RCH= NCH2CH2NH2 has been regioselectively synthesized under ultrasound irradiation in non polar solvents CCl4 with 92%-98% yields and characterized by NMR, MS, IR and ele- mental analysis. 1 H NMR and IR spectra showed that when recrystallized from ethanol or dried above 50℃ the transference of mono-Schiff bases 2a - d to Schiff bases la -d happened.