降低土霉素差向化反应的工艺改进研究

The Research on the Technological Improvement of Reduction of 4-Differentiation of OTC

从生产过程控制着手,考证了土霉素预处理过程中酸化pH值控制水平、过程温度控制水平和预处理时间长短对差向化反应产生影响程度,确定了温度、静置时间是影响4-差向土霉素含量提高的关键因素,设计进行了预冷水、发酵预先降温、冷冻酸化等试验研究,并验证了其有效性。

The degree to which the acidified value of pH, the temperature and the length of time of the preliminary treatment of OTC affect the differentiation in the productive processes is tested. The temperature and the length of time of the preliminary treatment of temperature and the length of time of the preliminary treatment of OTC in production. H is are determined. Research such as preliminary cooling of the water, preliminary loosening of the temperature and freezing acidification are conducted and then validity is also tested.