摘要
以氧头孢母核为起始原料,经酰基化、缩合反应结合两侧链,再用TFA脱去羧基保护,最终用NaHCO3转盐冻干制得氟氧头孢钠盐,总收率达42%。
Flomoxef sodium was synthesized from oxacephem nucleus by acidylate, condensation deprotection with TFA , invert to salt with NaHCO3 and lyophilization in an overall yield of 42%.
出处
《河北化工》
2006年第5期27-28,共2页
Hebei Chemical Industry
