慢性肾病患者听力损伤及血清微量元素与肾虚证关系的探讨

Study on Relation of Kidney-Deficiency with Hearing Damage and Serum Trace Elements in Patients with Chronic Nephropathy

本研究通过对７３例慢性肾病患者进行听力及血清微量元素测定，发现患者总高频听力障碍发生率为６８．５％，平均听力损伤３５．１±６．１ｄＢ：而有肾虚证表现的５５例患者中，高频听力障碍发生率为８３．６％，明显高于无肾虚证者（２２．２％）。有肾虚证表现患者血清微量元素铁、锌的含量也明显低于无肾虚证者及健康人，且血清铁含量降低的程度与听力损伤的程度成正比。在肾虚、血清微量元素铁、锌含量及听力损伤之间有着非常密切的内在联系。

The hearing and serum trace element of 73 cases of chronic nephropathy were measured.Results showed that the incidence of hearing damage in high frequency was 68.5% with a mean hypoacusis of 35.1±6.1 dB, while in 55 patients of Kidney Deficiency type, the incidence of hearing damage in high frequency was 83.6%, it was significantly higher than that in patients without Kidney Deficiency. The serum levels of trace elements(iron and zinc) in patients with Kidney Deficiency were lower than that of normal level and in patients without Kidney Deficiency. and the decrease of serum iron was directly proportional to the degree of hearing damage. There were close relationship between the Kidney Deficiency with the hearing damage as well as the serum levels of iron and zinc.