24小时眼压测量在疑似正常眼压性青光眼患者诊断的临床应用

Clinical Application of the 24 Hour IOP Monitoring in the Diagnose of the Normal Tension Glaucoma Suspects

目的:评价24h眼压测量在正常眼压性青光眼疑似患者诊断中的意义。方法:选择正常眼压性青光眼疑似患者51人(51只眼),进行24h眼压测量。结果:进入研究的51只眼中,只有18只眼(35.3%)的眼压在正常范围内且昼夜眼压波动小于6mmHg(1mmHg=0.133kPa),33只眼(64.7%)出现昼夜眼压波动过大或峰值眼压高于21mmHg。24h眼压的昼夜波动值、均值及峰值分别比门诊多次眼压高4.65mmHg、1.64mmHg及3.96mmHg,差异均具有统计学意义(P<0.001)。结论:24h眼压测量与门诊多次眼压相比,能更好地发现高眼压和昼夜眼压波动异常。

Purpose ： To determine the value of 24-hour IOP monitoring in routine clinical practice of the suspects of normal tension glaucoma（NTG）. Methods： Fifty-one suspects of NTG （51 eyes） were selected for 24-hour IOP monitoring without any antiglaucoma therapy. Results： In all of 51 eyes, there were only 18（35.3%） eyes＇s IOP kept in the statistic normal range and the IOP variation amplitude were under 6 mmHg, 33 eyes（64.7%） have large diurnal fluctuations in IOP or the peak IOP up to 21 mmHg. The mean of the IOP variation amplitude ,mean and peak of the 24-hour monitoring was 4.65 mm Hg, 1.64 mm Hg and 3.96 mm Hg higher than of the daytime IOP measurement （P 〈 0.001）. Conclusions ： Compared with the daytime IOP measurement, the 24-hour IOP monitoring could identify diurnal IOP and/or IOP spikes Better.