慢性胰腺炎196例的病因相关因素分析

Etiology-related factors of chronic pancreatitis: analysis of 196 clinical cases

目的探讨慢性胰腺炎的病因构成。方法回顾分析2001～2004年196例慢性胰腺炎患者的病因相关因素。结果仅有12例(6.12%)病因不明确,184例(93.88%)患者具有两种或两种以上的病因相关因素存在。其中患有胆道系统疾病116例次(26.73%),吸烟92例次(21.20%),长期饮酒79例次(18.20%),胰腺疾病97例次(22.35%),高脂血症40例次(9.22%),自身免疫疾病4例次(0.92%),高钙血症2例次(0.46%),营养不良2例次(0.46%),胰周血管动脉瘤2例次(0.46%)。结论在我国慢性胰腺炎的病因可能是多方面的,各种病因相关因素交织共同促使其发生。

Objective To investigate etiologyrelated factors of chronic pancreatitis. Methods 196 patients with chronic pancreatitis admitted in recent three years were analyzed retrospectively. Results Only 12 patients had no clear etiologic cause, and the remaining 184 patients had two or more etiologic causes, including biliary diseases in 116 patients （26. 73%）, smoking history in 92 patients （21. 20%）, alcohol abuse in 79 patients （18. 20%）, underlying pancreatic diseases in 97 patients （22.35%）, hyperlipemia in 40 patients （9. 22%）, autoimmune diseases in 4 patients （0. 96%）, hyperealeemia in 2 patients （0.46%）, malnutrition in 2 patients （0.46%）, and aneurysm in 2 patients （0. 46%）. Conclusions Chronic panereatitis may have multiple etiologic causes, chronic panereatitis in an individual patient may be attributed to several factors.