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Prevalence of occult HBV infection in haemodialysis patients with chronic HCV 被引量:7

Prevalence of occult HBV infection in haemodialysis patients with chronic HCV
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摘要 瞄准:与长期的 HCV 在血液透析病人学习流行和秘密 HBV 感染的临床的效果。方法:有否定 HbsAg 的五十个长期的牙齿过敏细胞溶解病人,和积极 anti-HCV 在学习被包括。这些病人被划分成二个组:积极的 HCV-RNA 和 HCV-RNA negative,基于 HCV-RNA PCR 的结果。HBV-DNA 在两个组用 PCR 方法被学习。结果:任何一个都没由 PCR 方法在浆液 22 个 HCV-RNA 积极病人和 28 个 HCV-RNA 否定病人揭示 HBV-DNA。平均年龄是 47.2 +/- 17.0 在 HCV-RNA 积极的组和 39.6 +/- , 15.6 在 HCV-RNA negative 组织。结论:秘密 HBV 感染的流行不在有在我们的区域的长期的 HCV 的血液透析病人高。我们的学习的这结果不得不在我们的区域在在 HBsAg 确实(8%-10%) 和 HBV 异种的频率之间的相互作用的考虑被评估。 AIM: To study the prevalence and clinical effects of occult HBV infection in haemodialysis patients with chronic HCV.METHODS: Fifty chronic hemodialysis patients with negative HbsAg, and positive anti-HCV were included in the study. These patients were divided into two groups: HCV-RNA positive and HCV-RNA negative, based on the results of HCV-RNA PCR. HBV-DNA was studied using the PCR method in both groups.RESULTS: None of the 22 HCV-RNA positive patients and 28 HCV-RNA negative patients revealed HBV-DNA in serum by PCR method. The average age was 47.2±17.0 in the HCV-RNA positive group and 39.6±15.6 in the HCV-RNA negative group.CONCLUSION: The prevalence of occult HBV infection is not high in haemodialysis patients with chronic HCV in our region. This result of our study has to be evaluated in consideration of the interaction between HBsAg positivity (8%-10%) and frequency of HBV mutants in our region.
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第21期3420-3424,共5页 世界胃肠病学杂志(英文版)
关键词 流行病学 乙型病毒肝炎 血液透析 丙型病毒肝炎 Chronic HCV Haemodialysis Occult HBV infection
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