PET/CT与CT显像对非小细胞肺癌诊断的对比研究

Comparative analysis of PET/CT vs CT scan in the diagnosis of non-small cell lung cancer

目的:通过PETECT与CT在NSCLC诊断中的对比研究,评价PETECT在诊断NSCLC及其转移灶的临床价值。材料与方法:收集经手术、CT引导下肺穿刺活检及随访证实的NSCLC56例。均行PETECT及CT扫描。行18F-FDGPETECT图像和CT图像对比研究。结果:56例NSCLC患者,对于肺原发灶,PETECT灵敏度96.4%,CT灵敏度82.1%,二者相比差异显著(P=0.008);对于转移灶,PETECT灵敏度100%,CT灵敏度80.5%,二者相比差异显著(P<0.001)。结论:PETECT在NSCLC原发病灶诊断及其转移灶的检出上优于CT显像。随着PETECT的普及,其有望成为肺癌无创诊断的新标准。

Objective： To explore the diagnostic value of dual-modality positron emission tomographic-computed tomographic （PET/CT） imaging, as compared with that of CT alone in the diagnosis of NSCLC and metastasis. Materials and Methods： Fifty-six cases of lung cancer were proved by surgery, biopsy, pathology or follow-up. All cases were examined by PET/CT and CT. PET/CT images of all patients were analyzed and compared with CT scan. Results： In 56 cases, for lung primary lesion, the positive rate with PET/CT scan was 96.4%, and CT scan was 82.1%. And for the metastatic lesion, the positive rate was 100% and 80.5% respectively. It was statistically significant（P=0.008 and P〈0.001）. Conclusion： PET/CT is superior to CT scan in the detection of primary lung lesions and metastasis. Integrated PET/CT becomes more widely available, it may become a new standard approach to imaging patients with lung cancer.