大肠癌肝转移与乙肝病毒感染关系

Relationship between Hepatic Metastasis and Hepatitis B Virus Infection in Colorectal Cancer

[目的]探讨乙肝病毒感染与大肠癌肝转移的关系。[方法]回顾性分析1991年6月￣2000年6月收治的大肠癌患者766例,比较乙肝病毒感染的大肠癌和非乙肝病毒感染的大肠癌两组肝转移的发生率。[结果]乙肝病毒感染组同时、异时肝转移发生率分别为9.2%和11.8%,非乙肝病毒感染组同时、异时肝转移发生率分别为22.7%和26.6%,两者相比差异有显著性(P<0.05)。[结论]乙肝病毒感染的大肠癌同时或异时肝转移发生率均比非乙肝病毒感染组低,前者很少发生肝转移。

[Purpose] To explore the relationship between HBV infection and hepatic metastasis in colorectal cancer. [Methods] Seven hundred and sixty six cases with colorectal cancer between Jun.1991 and Jun.2000 were retrospectively analyzed, and the prevalence of hepatic metastasis of colorectal cancer patients with and without hepatitis B virus infection was compared. [Results] In the HBV carriers＇ group, the prevalences of homochronous hepatic metastasis and heterochronous hepatic metastasis were 9.2% and 11.8% respectively. Meanwhile, in the non-HBV group, those were 22.7% and 26.6%, respectively. A significant difference between the two groups was found （P〈0.05）. [Conclusions] The prevalence of homochronous hepatic metastasis and heterochronous hepatic metastasis in colorectal cancer with HBV infection is lower than that in non HBV infection group. Hepatic metastasis is infrequent in HPV infected colorectal cancer.