氯丙嗪对肝胆损害的超声检查

Observation on Injury Affection of Liver and Bile caused by Chlorderazin

目的探讨抗精神病药物对患者肝系损害的情况,以指导临床用药。方法对长期服用氯丙嗪类药物的慢性精神分裂症病人肝胆系统的改变进行研究,将肝脏超声改变与肝功能损害的关系进行分析和探讨。结果两组呈显著性差异(P<0.01)。结论广泛应用B超对长期服用抗精神病药物患者肝胆系统的动态监测,具有重要的临床意义。

Objective To discuss the affection of antipsychotic drug for liver and bile system to indicate the therapy in clinic. Methods The clumges of liver and bile system were studied for the patient of chronic dementia who took the antipsychotic drug long time. The relationship of ultrasound clumge of liver and hepatic function were analyzed. Results There was significant difference between two groups （ P 〈 0.01）. Condusion The ultrasound detection for long term intake anfipsychotic drug patient might be important significance.