双水平正压通气呼吸机治疗肺结核并呼吸衰竭的疗效观察

Clinical effects of Bi-level positive airway pressure ventilation in pulmonary tuberculosis patients with respiratory failure

目的观察双水平正压通气呼吸机(BiPAP呼吸机)治疗肺结核合并呼吸衰竭的疗效。方法31例肺结核合并慢性呼吸衰竭为治疗组,20例为对照组。结果2组治疗后动脉血氧分压(PaO2)、血氧饱和度(SaO2)明显上升,治疗组血二氧化碳分压(PaCO2)比治疗前明显下降(P<0.01),呼吸困难明显减轻。结论用BiPAP呼吸机辅助通气治疗肺结核合并呼吸衰竭的疗效较好,可提高PaO2、降低PaCO2,预防肺性脑病的发生。

Objective To observe Bi-level positive airway pressure ventilation（BiPAP ventilation）the treatment effects in pulmonary tuberculosis patients with respiratory failure. Methods Thirty-one patients treated by BiPAP on the basis of routine treatment were enrolled in the treatment group. The efficacy was evaluated and compared with 20 similar patients is the control group. Results After BiPAP ventitalion the PaO2 and PaCO2 were greatly improved in treatment group（ P 〈 0.01 ）. PaO2 was also increased in control group. There was no significantly difference after routine therapy. Conclusion BiPAP ventitalion can improve the PaO2 and PaCO2 and relieve symptom especially to respiratory muscle fatigue. It is a supplementary measure to treat pulmonary tuberculosis patients with respiratory failure and it can prevent the incidence of pulmonary encephatopathy.