使用安定加催产素促进活跃期产程的临床观察

A Clinical Trial Of Valium And Oxytocin In Active Phase In Accelerating Labor Progress

目的探讨安定加催产素在活跃期促进产程进展的作用。方法把75例单胎头位的初产妇,且潜伏期均超过6小时者,随机分成研究组(38例),对照组(37例)。两组均于宫口开大3cm时,研究组应用静注安定10mg半小时后,加催产素3u+5%GS500ml静滴;对照组仅应用5%GS+催产素3u静滴。观察两组药物对促进产程进展效果的比较。结果研究组在用药至宫口开全、用药至分娩时间及第一产程、总产程均短于对照组,两组比较差异有显著性(P<0.01)。研究组的剖宫产率低于对照组,而阴道分娩率则高于对照组,两组比较差异有显著意义(P<0.05)。结论对于潜伏期较长的初产妇,在活跃期应用安定加催产素可明显促进产程的进展,提高阴道分娩率和降低剖宫产率。

Objective To explore the function of valium and oxytocin in promoting labor progress in active phase. Methods A total of 75 primipara with single fetus and vertex presentation, and the time length of the latent phase over 6 hours, were randomly divided into two groups. In the study group（38 cases）, each primipara was injected with oxytacin at half past an hour injected with valium. And each pfimipara in the control group （37 cases） was only injected with oxytocin. The effects of the two drugs were observed according to the function of accelerating progress of labor. Results It spended less time in the study group than in the control group in the progress of complete dilatation of cervix and labor time with medicine, first stage of labor, and total stage of labor. The difference was significant between the study group and the control group （P〈0.01）. A significant difference was noted that in the study group, the rate of cesarean was lower, while the rate of labor in vagina was higher than that of the control group. Conclusions Valium and oxytocin might accelerate labor progress obviously in active phase for primipara with the long latent phase. And they might also increase the rate of labor in vagina and decrease the rate of cesarean.