摘要
大量的文献表明,抑癌基因与细胞增殖调控密切相关,因此,它们与细胞衰老的关系已成为最近几年来人们研究的一个热门课题,p53、p21、p16、RB是目前研究比较深入的几个与细胞衰老相关的抑癌基因。
More and more studies show that tumor suppressor genes play important roles in the regulation of cell proliferation. "Therefore, the relationship between tumor suppressor genes and cell aging has been greatly highlighted in last decade,p53,p21 ,p16 and RB are some of those genes which are investigated more deeply and shown more relationship with cellular senescence.
出处
《医学综述》
2006年第12期711-713,共3页
Medical Recapitulate
关键词
细胞衰老
P53基因
P16基因
RB基因
抑癌基因
Cellular senescence
p53 gene
p16 gene
RB gene
Tumor suppressor genes(anti-oncngene)