1Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans[J]. Nature, 1998,391:806 - 811.
2Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function[J]. Cell,2004,116:281-297.
3Tijsterman M, Plasterk RHA. Dicers at RISC: the mechanism of RNAi[J]. Cell,2004,117:1 - 3.
4Meister G, Tuschl T. Mechanisrm of Gene Silencing by Double-stranded RNA[J]. Nature, 2004,431 : 343 - 349.
6Schwarz DS,Tomari Y,Zamore PD. The RNA-induced silencing complex is a Mg^2+ -dependent endonuclease[J]. Curr Biol, 2004,14:560-562.
7Lipardi C, Wei Q, Paterson BM. RNAi as random degradative PCR:siRNA primers convert mRNA into dsRNAs that are degraded to generate new siRNAs[ J ]. Cell, 2001,107: 297 - 307.
8Jones L, Ratcliff F, Baulcombe DC. RNA-directed transcriptional gene silencing in plants can be inherited independently of the RNA trigger Met1 for maintenance[J]. Curr Biol,2001,11(10):747 - 757.
9Xia HB, Mao Q, Parlson HL, et al. siRNA-mediated gene silencing in vitro and in vivo[J]. Nat Biotechnol,2002,20(10):1006-1010.
10Shirane D. Enzymatic production of RNAi libraries from cDNAs[J]. Nat Genet,2004,36:190 - 196.
二级参考文献19
1[1]Tijsterman M, Ketting RF, Plasterk RHA. The genetics of RNA silencing. Annu Rev Genet, 2002, 36 489～519.
3[3]Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev, 2001, 15 188～200.
4[4]Mcmanus MT, Sharp PA. Gene silencing in mammals by small interfering RNAs. Nature Reviews Genetics, 2002, 3 737～747.
5[5]McCaffrey AP, Meuse L, Pham TT, et al. Gene expression: RNA interference in adult mice. Nature, 2002, 418 38～39.
6[6]Xia HB, Mao Q, Parlson HL, et al. siRNA-mediated gene silencing in vitro and in vivo. Nature Biotechnology, 2002, 20 1006～1010.
7[7]Tiscornia G, Singer O, Ikawa M, et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. PNAS, 2003, 100 1844～1848.
8[8]Hasuwa H, Kaseda K, Einarsdottir T, et al. Small interfering RNA and gene silencing in transgenic mice and rats. FEBS lett, 2002, 532 227～230.
9[9]Pekarik V, Bourikas D, Miglino N, et al. Screening for gene function in chicken embryo using RNAi and electroporation. Nature Biotechnology, 2003, 21 93～96.
10[10]McCaffrey AP, Nakai H, Pandey K, et al. Inhibition of hepatitis B virus in mice by RNA interference. Nature Biotechnology, 2003, 21 639～644.
