眼晶体中某些元素含量与白内障关系的研究

A Study of relationship between senile cataract and contents of some elements in human eye lenses

用中子活化分析法测定了正常人眼晶体及老年性白内障晶体中的Ｋ、Ｃａ、Ｎａ、Ｃｌ、Ｓ、Ｓｅ、Ｚｎ、Ｍｇ．Ｆｅ、Ｒｂ、Ｃｓ、Ｃｒ、Ｃｏ、Ｃｅ、Ｍｎ、Ｓｂ、Ｓｃ、Ｅｕ和Ｔｈ等１９种元素的含量，发现在白内障晶体中Ｃａ、Ｎａ、Ｃｌ、Ｅｕ、Ｓｂ、Ｆｅ等元素含量显著高于正常晶体；Ｋ、Ｒｂ、Ｃｓ、Ｃｒ、Ｍｎ、Ｃｏ、Ｓｃ和Ｃｅ等元素含量显著低于正常晶体。其中Ｎａ、Ｃｌ、Ｃａ之间；Ｋ、Ｒｂ、Ｃｓ之间存在显著性正相关。Ｎａ、Ｃｌ、Ｃａ与Ｋ、Ｒｂ、Ｃｓ之间存在显著性负相关。提示眼晶体中Ｃａ、Ｎａ、Ｃｌ的蓄积和Ｋ的丢失可能是白内障形成的直接原因。微量元素Ｆｅ、Ｃｒ、Ｃｏ、Ｍｎ、Ｒｂ、Ｃｓ等在白内障形成过程中也可能发挥着一定的作用。

Neutron activation analysis was used to determine the concentrations of 19 elements in normal and senile cataractous eye lenses. It was found that the concentrations of Ca,Na,Cl,Eu,Sb and Fe were significantly higher, but those of K,Rb,Cs,Cr,Mn,Co,Sc and Ce were significantly lower in senile mature cataractous lenses than those in normal human eye lenses. There was no obvious difference for the concentrations of Se,Zn,Mg,S and Th in the two groups.The positive correlations among Na,Cl and Ca,K,Rb and Cs were shown, whereas a significant negative correlation between Na,Ca,Cl and K,Rb,Cs was observed. The roles of these elements in the evolution of cataract are discussed.