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原发性高血压病患者血清SOD的改变以及海捷亚的干预效果 被引量:1

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摘要 目的观察原发性高血压病患者抗氧化酶系统的变化以及海捷亚的干预效果。方法选择原发性高血压病人60例,随机分为海捷亚组30例和对照组(非洛地平)30例,治疗4周,分别检测治疗前后患者血压和血清超氧化物歧化酶(SOD)的活力变化,并用30例健康体检者的血清做参考。结果治疗后,两组平均动脉压血压均明显下降,但海捷亚组下降更明显(P<0.05);而两组SOD的含量都增加,但海捷亚组SOD的升高却较对照组明显(t=2.68,P<0.01)。结论海捷亚除对原发性高血压病患者具有良好的降压效果外,还能够增加患者的SOD活力,清除过多的氧自由基,防止血管内皮细胞的脂质过氧化。
出处 《临床医学》 CAS 2006年第6期23-24,共2页 Clinical Medicine
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