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胃肠道间质瘤复发原因和预后因素分析 被引量:1

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摘要 目的分析胃肠道间质瘤(gastro intestinal strom al tumors,G IST)的手术治疗效果及其影响复发和生存的因素。方法回顾1999年1月至2005年1月我院外科手术治疗的32例G IST患者的临床资料、病理诊断、免疫组织化学表达情况及手术过程并加以随访,分析手术治疗的效果及影响术后复发和生存率的因素。结果肿瘤直径<5 cm、≥5 cm、≥10 cm的复发率分别为0、20%、44.4%(P<0.05),全组中位生存时间为60.2个月,术后3年和5年生存率分别为70.6%和53.0%。肿瘤直径<5 cm患者的3年生存率显著高于≥5 cm者(P<0.05),复发组3年生存率显著低于未复发组(P<0.01),CD34阳性与阴性组患者的3年生存率差异无统计学意义(P>0.05)。结论G IST的预后与肿瘤大小、手术范围、手术的无瘤原则有密切关系。手术是G IST的首要治疗手段,可根据术中冷冻切片报告和肿瘤大小决定切除范围,免疫表型不能作为G IST的预后因素。
作者 陈平
出处 《临床医学》 CAS 2006年第6期32-34,共3页 Clinical Medicine
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  • 1杨其昌,季晓华,沈屹,韩枋,张晓娟,刘宏斌.74例胃肠道间质瘤临床病理与生物学行为评价[J].中华病理学杂志,2005,34(1):6-10. 被引量:68
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