41例乳腺分叶状肿瘤的诊断和治疗

The Diagnosis and Treatment of Phyllodes Tumor of the Breast: Report of 41 Cases

目的探讨乳腺分叶状肿瘤的临床表现、病理特点、治疗原则和影响预后的因素.方法回顾1997年6月至2005年6月收治的41例乳腺分叶状肿瘤患者的临床资料.结果41例患者平均年龄35岁,其中良性20例,恶性16例,交界性5例.19例行局部广泛切除术,7例行局部切除术,9例行单纯乳房切除术,6例行乳腺癌改良根治术;4例患者给予术后放疗.随访35例,平均随访26个月(5～101个月),1例术后3a死于远处转移,2例行局部切除术后复发.结论合理的手术方式是治疗乳腺分叶状肿瘤的方法.

Objective To study the clinical manifestation, pathological character, treatment strategies and prognostic factors of phyllodes tumor of breast . Methods We retrospectively reviewed 41 patients with breast phyllodes tumor. Results The average age was 35. Among all the patients, there were 20 benign cases, 5 borderline cases, 16 malignant cases. 19 patients received extensive local excision, 7 patients received local excision, 9 patients received simple mastectomy of breast and 6 patients were treated with modified radical operation. There were 4 patients undergoing radiotherapy after the operation. Follow - up was obtained for 35 cases, with an average of 26 months （5 - 101 months）, one of the patients died of metastasis 3 years after the operation, two patients suffered from local recurrence. Conclusions Appropriate operation is the most important prognostic factor of breast phyllodes tumor.