PC机辅助MR脑灌注成像初步研究

MR Cerebral Perfusion Imaging on Personal Computer

目的:研究PC机辅助MR脑灌注成像软件,探讨其临床应用价值。方法:在PC机上使用MR脑灌注成像软件,对5例健康人和18例脑缺血患者的灌注图像进行后处理,计算出有关脑灌注参数图,包括相对脑血流量(rrCBF)图、相对脑血容量(rrCBV)图、局部灌注达峰时间(TTP)图和团注平均通过时间(bMTT)图。结果:应用MR脑灌注成像软件可以在PC机上实现灌注图像的后处理,脑灌注参数图能够为脑缺血患者提供有价值的脑血液动力学信息,显示灌注异常的范围。结论:PC机辅助MR脑灌注成像软件简单易行,可显示常规MR无法显示的血流动力学异常,对临床和科研具有重要价值。

Objective：To introduce a method of making MR cerebral perfusion weighted imaging based on Personal Computer （PC） and probe into the clinical diagnostic value of the method. Methods： MR cerebral perfusion weighted imaging was performed in 5 normal adults and 18 patients with cerebral ischemia. Perfusion-weighted images were analyzed with a software running on PC. Cerebral perfusion mapping with parameters including relative regional cerebral blood flow （rrCBF）, relative regional cerebral blood volume （rrCBV）,time to peak （TTP） and bolus mean transit time （bMTT） were conducted on PC. Results：The process and analysis could be performed successfully on PC. The cerebral perfusion mapping provided valuable hemodynamic information and showed the extent of perfusion disturbances. Conclusion：PC aided mapping of MR cerebral perfusion weighted imaging is a simple and accessible technique for delineating the hemodynamic abnormalities. The methods could obtain more diagnostic information,and has great practical value in both clinical and research workes.