灵芝治疗鹅膏毒蕈中毒的疗效观察

Observation on Therapeutic Effect of Ganoderma Lucidum for the Poisoning Patients with Amanita Mushroom

目的 探讨灵芝对鹅膏毒草中毒病人的治疗作用。方法 将鹅膏毒草中毒病人76例随机分为实验组（40例）和对照组（36例）。对照组给予常规治疗。实验组在常规治疗基础上，加用灵芝煎液口服。比较两组的临床疗效及内脏损害情况。结果 实验组临床疗效明显优于对照组（P〈0．05）。两组谷丙转氨酶（ALT）、谷草转氨酶（AST）、尿素氮（BUN）、肌酐（SCr）4项指标均上升。实验组在第3天4项指标上升达高峰，以后逐渐下降；对照组ALT、AST指标则呈上升趋势。两组4项指标在相同时间比较。实验组明显低于对照组，有显著性差异（P〈0.05）。结论 灵芝对鹅膏毒草中毒有较好的治疗作用，能明显降低鹅膏毒蕈中毒的病死率。

Objective To observe the therapeutic effect of Ganoderma Lucidum on the patients with amanita mushroom poisoning. Methods 76 cases with amanita mushroom poisoning were randomly divided into control group （36 cases） treated by conventional therapy and test group （40 cases） treated by Ganoderma Lucidum Decoction combined with conventional therapy. Results The therapeutic effect in test group was significantly superior to that in control group （ P 〈 0,05）, The levels of alanine aminotransferase （ALT） ,aspartate aminotransferase （AST） ,blood urea nitrogen （BUN） and serum creatinine （SCr） were all obviously increased in the two groups of patients with amanita mushroom poisoning, getting to the peak value at the third day among cases in the second group. Then, they were significantly reduced in the test group. In contrast, ALT and AST increased in control group. The total levels of ALT, AST, BUN and SCr were obviously lower in test group than in control one on the same day. Conclusions Ganoderma Lucidum is very effective in the treatment of patients with amartita mushroom poisoning and can remarkably decrease the mortality of this lesion.