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黄芪注射液加地高辛治疗慢性充血性心功能不全疗效观察 被引量:2

The curative effect of the treatment of chronic congesive cardial deficiency by Astragalue injection and Digoxin
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摘要 目的:观察黄芪注射液加地高辛治疗慢性充血性心功能不全的疗效。方法:慢性充血性心功能不全病例57例,随机分为治疗组32例,年龄40~76岁,平均55.2±13.6岁。男性20例,女性12例;观察组25例,男性14例,女性11例,年龄42~74岁,平均53.6±5岁。心功能分级按美国纽约心脏病学会(NYHA)分级标准分为IV级。治疗组IV15例,Ⅲ级17例;对照组IV级10例,Ⅲ级15例。病因:治疗组冠心病7例、扩张性心肌病5例、高心病8例、风心病7例、肺心病5例;对照组:冠心病5例、扩张性心肌病3例、高心病6例、风心病7例、肺心病4例。两组之间病因及病情严重程度无显著差异。治疗组用黄芪注射液50ml加入200ml葡萄糖注射液中静脉点滴,地高辛0.25mg/d口服,7天后改为0.125mg/d,同时用卡托普利、利尿剂14天为一疗程。观察组地高辛卡托普利、利尿剂用法同治疗组。结果:治疗组显效5例为15.6%,有效17例为53.1%,有效率为68.7%。无效10例31.3%。观察组显效2例为8%,有效12例为48%,有效率为56%,无效11例为44%。两组比较有显著差异。结论:黄芪注射液加地高辛治疗慢性充血性心功能不全有明显的作用。 Objective. Observing the effect of chronic congestive cardial deficiency by Astragalue injection and Digoxin. Methods: 57 cases of chronic congested heart deficiency were randomly divided into treatment group, 32cases, age 40-76, average 55. 2±13.6 year old, 40 males and 12 females; and the observation group; 25 cases, 14 males and 11 females, age 42-74, average 53. 6±11.5. The heart functions were graded into Ⅳ levels according to the standard of New York Heart Disease Academy(NYHA). There were 15 cases of Ⅳ level, 17 cases of Ⅲ level in treatment group; 10 cases of Ⅳ level, 15 cases of Ⅲ level in comparison group. In treatment group: 7 cases of coronary heart disease, five cases with dilatatien cardiac muscle disease, 8 cases ;th hypertension heart disease, 7 cases with rheumatic heart disease, 5 cases with lung heart disease; comparison group: 5 cases with coronary disease, 3 cases of dilatation cardiac muscle disease, 6 cases of hypertension heart disease, 7 cases of rheumatic heart disease, 4 cases of lung heart disease. The pathogeny and severity degree of in these two groups were no remarkable difference. In treatment group, 50ml Astragalus injection liquid added into 200ml glucose injection adminisfered inflavenouely, Digoxin 0. 25mg/d were taken orally, and changed to 0. 125mg/d 7 days later, using captopril and hydragoguethe at the same time, 14 days for one period of treatment. The usage of digoxin,captopril and hydragoguethe in observation group is the same with treatment group. Results: In treatment group, 5 cases achieved obvious effects(15. 6%) ; 17 cases were effective(53.1%), the efficiency rate was 68. 7%. 10 cases were ineffective(31.3%). In observation group, 2 cases achieved obvious effects(8%);12 cases were effective(48%). The efficiency rate was 56%. 11 cases were ineffective(44%). The two groups showed remarkable difference (P〈0. 05). Conclusion: Astragalus injection added by digoxin has an obvious effect towards the treatment of chronic congestive cardial dysfunction.
出处 《四川生理科学杂志》 2006年第2期81-83,共3页 Sichuan Journal of Physiological Sciences
关键词 黄芪注射液 地高辛 慢性充血性心功能不全 Astragalus injection digoxin hyaragoguelth chronic congestive cadial dysfunction
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  • 1胡朝阳,杨芳炬.注射用黄芪冻干粉对大鼠心脏缺血的保护作用及分子机制[J].四川生理科学杂志,2005,27(3):142-143.

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