菟丝子对小鼠免疫功能影响的实验研究

目的探讨菟丝子对小鼠免疫功能的影响。方法将昆明种小鼠50只分为阴性对照组、阳性对照组、低剂量组、中剂量组、高剂量组。给药8d后测定各组动物脏器系数、腹腔巨噬细胞吞噬功能、脾淋巴细胞增殖反应、白介素活性。结果菟丝子可促进小鼠免疫器官脾脏、胸腺增长(P<0.05),并提高巨噬细胞吞噬功能(P<0.05);促进淋巴细胞增殖反应(P<0.05);诱导白介素产生。结论菟丝子具有增强小鼠机体免疫功能和免疫调节作用。

Objective To explore the cuscuta seed＇s effect on mice immune system . Methods 50 mice were divided into 5 groups ： negative control group ,positive control group, low dose group , medium dose group ,high dose . Coefficient of animal organs in all groups and phagocytosis function of macrophagocyte in abdomen cavity , cell multiplication of splenic lymphocyte ,interleukin＇s activity . Results cuscuta seed could promote the growth of mice＇s immune organs such as spleen and thymus gland （P 〈 0.05） and improve the phagocytosis thnction of macrophagocyte（ P 〈 0.05）; also it could stimulate the cell multiplication of splenic lymphocyte and induce the production of ieterleukin. Conclusion cuscuta seed could regulate and strengthen the mice＇s immune function.