基因表达系列分析研究进展

The Research Progress of Serial Analysis of Gene Expression

由于基因组计划的进展,基因组学的研究已从结构基因组学转向功能基因组学。作为一种新的研究基因表达的有效工具,基因表达系列分析(SerialAnalysisofGene,SAGE)技术能同时对大量的转录物进行定性和定量分析。本文介绍了SAGE的工作原理和实验路线,以及最新的技术进展和应用。

For the progress of Genome Program, the genome research has changed from structure genome to function genome. As a new effective tool in studying genome expression, Serial Analysis of C, ene Expression,SAGE） can do qualitative and quantitative analysis to a great deal of transcripts at the same time. This article reviews the principles, characteristic, experiment rout of SAGE and new technology advances and applications.