[Bmim][Br_3]与羰基化合物的选择性溴化反应研究

Selective α-Monobromination of Oxo-compound with [Bmim][Br_3]

研究了离子液体三溴化1-丁基-3-甲基咪唑[Bmim][Br3]对2-戊酮、4-甲基苯乙酮、4-甲氧基苯乙酮、6-甲氧基-2-乙酰基萘、2，2，5，5-4-甲基-3-己酮、环辛酮、环十二酮、丁醛等羰基化合物的α-溴化反应。在无催化剂、溶剂条件下，三溴化1-丁基-3-甲基咪唑[Bmim][Br3]对以上几种羰基化合物溴化。高产率、高选择性地得到α-溴化产物，产率为88％～94％。实验结果表明，在离子液体[Bmim][Br3]存在下，溴化反应不仅速度较快、温度缓和、操作简便，而且产物的产率高，易分离，对环境更友好。

The α-monobromination of 2-pentone, 4-methyl acetophenone, 4-methoxyacetophenone, 6-methoxy-2- acetylnaphthane, 2,2,5,5-tetramethyl-3-hexanone, cyclooctanone, cyclododecanone with [ Bmim] [ Br3 ] respectively, were studied. Under the solvent-free conditions, the product yields of above oxo-compounds were 88 % 494 % respectively with high selectivity. The results showed that in the presence of [Bmim] [Br3], the monobromination had many advantages, such as rapid reaction speed, easy to operation and separation, high yield and selectivity, and so on.