东南沿海某部皮肤真菌病流行病学调查及药敏试验

Epidemiology of dermatomycoses and susceptibility test in a troops of the south-east China

目的:摸清该地区部队皮肤真菌病发病情况及菌种分布,筛选出高效、经济、实用的外用抗真菌药物。方法:对选定部队进行皮肤真菌病流行病学调查,采集标本,用改良KANE/FISCHER皮肤癣菌鉴定系统对采集的标本进行菌种分离和鉴定,并依据NCCLS2003年版M38-A方案对所分离菌种进行药敏试验。结果:该部队皮肤真菌病发病率为29.80%,其中足癣占75.31%,菌种主要为红色毛癣菌(73.30%)和须癣毛癣菌(21.21%)。所选8种药物对受试真菌均有较好的敏感性。结论:该部队皮肤真菌病发病率高,红色毛癣菌为主要致病菌,8种药物的MIC之间的差异有显著性,特比奈芬、布替奈芬为较适宜的药物。

Objective：To identify the etiological and epidemiological factors of dermatophyte infections in the South-East China, to filtrate suitable chugs in the troops. Methods ： Use improved KANE/FISCHER system to identify the dermatophyte. To determine the Minimum Inhibitory Concentration （MIC） with the National Committee for Clinical Laboratory Standards （NCCLS） approved standard broth microdilution method （M38-A）. Results：The prevalence of dermatomycoses was 29.80%. tinea pedis was the most（75.31% ）. Trichophyton rubrum was the most frequent dermatophyte . All the 8 kinds of drugs were sensitive to the isolates. Conclusions：Trichophyton rubrum was the most frequent dermatophyte. There were significant differences among these 8 kinds of drugs. Terbinafine and Butenafine was the suitable drugs.