摘要
目的研究放射性125I粒子源治疗前列腺癌的剂量分布。方法采用三维治疗计划系统(3-DTPS)进行实验模拟,前列腺癌用肿瘤模型代替,应用热释光剂量学方法,模拟测量前列腺癌中的剂量分布。结果实验表明,125I粒子源治疗前列腺癌是在不均匀剂量模式下受照,剂量直接与粒子源的数量和几何位置有关。结论125I粒子源表面剂量最高,随着距离增加而剂量迅速下降。粒子源的间距越小瘤内剂量越高。
Objective To study the dose distribution of ^125Ⅰseeds in interstitial brachytherapy prostate cancer. Methods Tumour phantom（Ф50 ×15mm） was used by employing. 3-D the treatment planning system（3-D TPS） in the experiment simulation. Dose distribution of prostate cancer was determined in tumour phantom using thermoluminescence dosimetry method （TLD）. Results The experimental results indicated that dose distribution was nonuniform. We find the dose distributions of prostate cancer was relatecl with geometric configuration and the number of ^125Ⅰseeds. Conclusion The dose of ^125Ⅰseed source over the surface is the highest which attenuated very rapidly with distance;. The narrower the interstitial space of seeds, the higher the dose in the cancer.
出处
《中国辐射卫生》
北大核心
2006年第2期161-163,共3页
Chinese Journal of Radiological Health
基金
天津市自然基金(批准号043608111)
