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罕见的原发性浆细胞白血病神经系统复发 被引量:1

Nervous system relapse in primary plasma cell leukemia
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摘要 目的提高对原发性浆细胞白血病的认识。方法病例报告及文献复习。结果本报道及文献中共有6例原发性浆细胞白血病病人神经系统复发,其中免疫球蛋白IgG型3例、IgD型2例。神经系统临床表现各不相同,出现神经系统复发症状距起病的平均时间间隔为16.5个月。4例复发时行脑脊液检查均发现有浆细胞存在。出现神经系统侵犯后平均存活时间为6.7个月。结论神经系统是原发性浆细胞白血病的一个少见的髓外侵犯部位,预后极差。 Objective To improve the anderstanding of clinical profile of primary plasma cell leukemia. Methods Case report and literature review. Results A rare ease of nervous system relapse in primary plasma cell leukemia was reported. Six patients were identified from the literature. The type of immuuoglobulin included IgG (3 patients), IgD (2 patients). Clinical manifestations of nervous system were variable. The average interval from initial diagnosis to the development of nervous system relapse was 16. 5 months. Plasma cells were found in eerebrospinal fluid in 4 patients. The mean surviaval time was 6. 7 months after nervous system relapse. Coulusion Nervous system relapse in primary plasma cell leukemia is rare with poor prognosis.
出处 《基础医学与临床》 CSCD 北大核心 2006年第6期644-646,共3页 Basic and Clinical Medicine
关键词 原发性浆细胞白血病 神经系统复发 primary plasma cell leukemia nervous system replapse
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