复方丹参滴丸对大鼠血小板聚集功能的影响

Effect of Fufang Danshen Diwan to Platelet Aggregation Function

目的:研究复方丹参滴丸对大鼠血小板聚集的影响。方法:采用Born比浊法测定血小板聚集性,从而全面的分析血小板的聚集性能。结果:复方丹参滴丸对ADP和凝血酶诱导的血小板聚集的抑制作用,小剂量组差异显著(P<0.05),中剂量和大剂量组差异非常显著(P<0.01)。对胶原诱导的血小板聚集的抑制作用,中剂量组差异显著(P<0.05),大剂量组差异非常显著(P<0.01)。结论:复方丹参滴丸对ADP、凝血酶和胶原诱发的大鼠血小板聚集均有明显的抑制作用,且呈剂量依赖关系。

Objective：To study the effect of Fufang Danshen Diwan for the platelet aggregation function. Methods ：The platelet aggregation was measured by Born-nephelometer. Results： Three doses Fufang Danshen Diwan could inhibit platelet aggregation induced by ADP and thrombin,middle and high doses Fufang Danshen Diwan could inhibit platelet aggregation induced by collagen. Conclusion：Fufang Danshen Diwan can inhibit platelet aggregation induced by ADP,collagen and thrombin.