摘要
目的 评价雷帕霉素洗脱支架在冠心病患者中应用1年后的疗效。方法 73例冠心病合并2型糖尿病患者置入雷帕霉素药物支架101枚,11枚(10.9%)为直接置入,其余90枚(89.1%)在置入前给予球囊预扩张。支架释放压力为8~16个大气压,其中39例(38.6%)进行了后扩张。所有患者术前、术后给予足量抗血小板药物。结果 手术成功率99.3%,73例患者均完成随访。平均随访时间为(15.4±3.5)个月。复发心绞痛6例(8.2%),急性心肌梗死1例(1,3%)。均接受了运动平板检查,其中阳性19例(26,0%),仅3例因为胸痛发作停止运动试验。19例(26.0%)运动平板结果阳性的患者在术后6~12个月内进行了冠状动脉造影复查。5例患者为药物支架内再狭窄,其中4例给予再次血管成形术。结论 雷帕霉素洗脱支架临床应用的远期效果良好,可减少再狭窄的发生。
Objective To evaluate the long term outcomes of rapamycin eluting stent in patients with coronary heart disease and diabetes one year later. Methods 73 CHD patients complicated with type 2 diabetes were treated with 101 rapamycin eluting stents. 11 (10.9% ) stents were implanted directly and the other 90 ( 89.1% ) was implanted with predilation. And postdilation was performed in 39 patients ( 38.6% ). The stent was delivered within the pressure 8 to 16atm. All patients received aspirin and clopidogrel regularly before and after the procedure. Results Procedural success rate reached 99.3%, with completion of the follow-up in all the patients, averaging ( 15.4 ± 3.5 ) months. 6 patients suffered recurrent angina ( 8.2% ) and 1 had acute myocardial infarction ( 1. 3% ). All patients received Hoher exercise showing that the result of 19 patients was positive (26.0% ) ,3 of who stopped exercise because of chest pain attack. The 19 cases received coronary artery angiography for reexamination within 6-12 months after operation. 5 patients had in-stent restenesis ,of who 4 received revaseularization. Conclusion Rapamycin eluting stent can be used safely and effectively, with better long-term results, which can reduce restenosis rate.
出处
《中国医药》
2006年第4期196-197,共2页
China Medicine
关键词
冠心病
糖尿病
药物洗脱支架
Coronary heart disease
Diabetes
Rapamycin eluting stent