1Lyman SD. Biologic effects and potential clinical applications of Flt3 ligand. Curr Opin Hematol, 1998,5:192
2Lyman SD. James L, Bos TV, et al. Molecular of a ligand for the Fh3/flk-2 tyrosine kinase recerptor: A proliferative factor for primitive hematopoietie cells. Cell, 1993,75:1157
3Ito A, Hirota S, Kitamura Y, et al. Developmental expression of flt3 mRNA in the mouse brain. J Mol Neurosci, 1993,4(4):235
4Brasel K, Escobar S, Anderberg R, et al. Expression of the flt3 receptor and its ligand on hematopoietic cells. Leukemia, 1995,9(7):1212
5Rottapel R, Turck CW, Casteran N, et al. Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the routine Flt3 receptor tyrosine kinase. Oncogene,1994, 9(6):1755
6Broxmeyer HE,Lu L, Cooper S,et al. Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells.Exp Hematol,1995, 23(10):1121
7Ashihara E,Shimazaki C, Sudo Y, et al. FLT-3 ligand mobilizes hematopoietic primitive and committed progenitor cells into blood in mice. Eur J Haematol, 1998, 60(2):86
8Chen K, Braun S,Lyman S,et al. Antitumor activity and immuno-therapeutic properties of Flt3-ligand in a murine breast cancer model. Cancer Res, 1997,57:3511
9Bello-Femandez C,Natyash M,Strobl H,et al.Efficient retrovirus-mediated gene transfer of dendritic cells generated from CD34+ cord blood cells under serum-free conditions. Hum Gene Ther,1997,8:1651
10Peron JM,Esche C,Subbotin VM,et al. Flt-ligand administration inhibits liver metastases: Role of NK cells.J Immunol,1998,161:6164
5Broxmeyer HE,Lu L,Cooper S,et al.Flt3 ligand stimulates/costimulates the growth of myeloid stem/progenitor cells[J].Exp Hematol,1995,23:1121-1129.
6Rusten LS,Lyman SD,Veiby OP,et al.The Flt3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34 bone marrow progenitor cells in vitro[J].Blood,1996,87:1317-1325.
7Papayannopoulou T,Nakamoto B,Andrews RG,et al.In vivo effects of Flt3/Flk2 ligand on mobilization of hematopoietic progenitors in primates and potent synergistic enhancement with granulocyte colony stimulating factor[J].Blood,1997,90:620-629.
8Lynch DH.Induction of dendritic cells (DC) by Flt3 ligand (FL)promotes the generation of tumor specific immune responses in vive[J].Crit Rev Immumol,1998,18:99-107.
9Lyman SD,James L,Johnson L,et al.Cloning of the human homologue of the murine Flt3 ligand:a growth factor for early hematopoietic progenitor cells[J].Blood,1994,83 (10):2795-2801.
10Lyman SD,Stocking K,Fletcher F,et al.Structural analysis of human and murine flt3 ligand genomic loci[J].Oncogene,1995,11:1165-1172.