腹部肥胖人群大动脉弹性变化的研究

Study on the change of large arterial function in belly obesity Persons

目的研究健康人群脂肪分布与大动脉弹性变化的关系。方法的226例门诊体检的入选者分别测量其血压、身高、体重和腰围,根据腰围>85 cm(男),腰围>80 cm(女),分为腹部肥胖组及非腹部肥胖组。应用法国Artech-Medical公司研制生产的脉搏波速度测定仪———专家型康普乐(Complior SP)同时测定颈动脉-桡动脉(C-RPWV),颈动脉-股动脉的脉搏波速度(C-FPWV)。结果腹部肥胖组的C-RPWV与C-FPWV(C-RPWV:9.35 m/s,C-FPWV:9.37 m/s)均快于非腹部肥胖组(C-RPWV:9.00 m/s,C-FPWV:9.19 m/s),但没有达到统计学差异。C-RPWV与腰围(r=0.236,P<0.001),C-FPWV与腰围(r=0.159,P<0.05)呈正相关。结论腹部肥胖是影响大动脉弹性的重要因素。

Objective To study the relationships of large arterial in healthy persons. Methods 316 appearance healthy subjects＇ blood pressure parameters, height, waist around were measured. According to waist around, whether is large than 85cm （male）, 80cm （female） or not, all subjects were divided into two groups （belly obesity groups or non-belly obesity groups）. These were measured by the Complior SP including carotid-radial （C-R） PWV and carotid-femoral （C-F） PWV. Results The mean C-RPWV and C-FPWV[-（9.35±1.54 and 9.37±1.54）m/s] in belly obesity group were greater than that of non- non-belly obesity groups[-（9.00±1.27 and 9.19±1.62）m/s], but the comparison had no statistic significance （P 〈 0.05.）. C-RPWV and C-FPWV were correlated with waist around. Conclusions Belly obesity is one of important factors for large arterial function.