重组生长激素在肝胆外科老年病人术后恢复中的应用价值

Applied value of rhGH using in hepatobiliary surgery for postoperative recovery of the elder patients

目的评价重组生长激素在肝胆外科老年病人术后恢复中应用的疗效。方法2004年1月到2004年12月在3间不同医院的肝胆外科中选择腹腔镜胆囊切除的65岁以上的患者共40人,随机分为实验组和对照组,每组各20人。分别应用重组生长激素4单位四天和生理盐水四天。于术前两天,术后一天,术后三天,术后一周,术后两周作为观察点。结果两组在总住院天数,白蛋白水平,双手握力,疲劳评分等方面改善有明显差异,试验组明显优于对照组。结论在老年病人腹部手术后应用生长激素能缩短住院时间,提高营养水平,能明显改善术后疲劳综合征的程度。

Objective To evaluate the curative effects of recombinant human growth hormone （rhGH） for postoperative recovery of elder patients of hepatobiliary surgery. Methods From January 2004 to December 2004, 40 cases over 65 years received laparoscopic cholecystectomy were selected in the three different hospitals.These patients were randomly divided into experimental group and control group （every group was 20 patients）. The rhGH 4 u and normal saline were used to 4 days after operation respectively. Observed time point was in 2 days before operation and 1,3,7, 14 days after operation respectively.Results The total hospitalization, albumin level, muscle strength and fatigue score had significant difference in two groups. The experimental group was much superior to the control group.Conclusion when the rhGH is used in the postoperative senile patients of abdominal surgery, it can shorten hospitalization, enhance nutrition level and improve postoperative fatigue syndrome.