摘要
目的:研究麻黄汤(MHT)不同配伍对大鼠额叶皮层中Asp氨基酸类神经递质含量的影响。方法:2,4二硝基氟苯为衍生化试剂,HPLC/UV法测定Asp的含量。结果:在0.05水平下,桂枝显著降低了天冬氨酸的含量(P=0.032);杏仁、甘草的影响不显著(P=0.149,P=0.095);甘草与桂枝呈显著降低的一级交互作用(P=0.017)。结论:桂枝是影响天冬氨酸含量的显著性因素,而杏仁、甘草的影响不显著。
Objective: To study the influence of the different compatibility of Mahuang Tang (MHT) on the content of Asp in the prefrontal cortex of the rats, analyze the meaning of compatibility. Methods: Use 2,4-dinitrofluorobenzene as derivatizing agent, HPLC/UV to determine the content of Asp. Results: At the 0.05 level, Ramulus Cinnamomi had significantly reduced the contents of Asp( P = 0. 032 ), the effect of Semen Armeniacae and Radix Glycyrrhizae had no statistical meaning( P = 0. 149,P = 0. 095, respectively). Ramulus Cinnamomi and Radix Glycyrrhizae had significant two-way interaction (P = 0. 017 ). Conclusion : Ramulus Cinnamomi is the significant effect factor on the the contents of Asp, but the effect of Semen Armeniacae and Radix Glycynbizae is not significant.
出处
《中药药理与临床》
CAS
CSCD
北大核心
2006年第1期1-2,共2页
Pharmacology and Clinics of Chinese Materia Medica
关键词
麻黄汤
配伍
天冬氨酸
Mahuang Tang( 麻黄汤 )
compatibility
aspartic acid