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麻黄汤不同配伍对大鼠大脑皮层额叶天冬氨酸含量的影响 被引量:5

Influence of the different compatibility of Mahuang Tang (麻黄汤) on the content of Asp in the prefrontal cortex of rats
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摘要 目的:研究麻黄汤(MHT)不同配伍对大鼠额叶皮层中Asp氨基酸类神经递质含量的影响。方法:2,4二硝基氟苯为衍生化试剂,HPLC/UV法测定Asp的含量。结果:在0.05水平下,桂枝显著降低了天冬氨酸的含量(P=0.032);杏仁、甘草的影响不显著(P=0.149,P=0.095);甘草与桂枝呈显著降低的一级交互作用(P=0.017)。结论:桂枝是影响天冬氨酸含量的显著性因素,而杏仁、甘草的影响不显著。 Objective: To study the influence of the different compatibility of Mahuang Tang (MHT) on the content of Asp in the prefrontal cortex of the rats, analyze the meaning of compatibility. Methods: Use 2,4-dinitrofluorobenzene as derivatizing agent, HPLC/UV to determine the content of Asp. Results: At the 0.05 level, Ramulus Cinnamomi had significantly reduced the contents of Asp( P = 0. 032 ), the effect of Semen Armeniacae and Radix Glycyrrhizae had no statistical meaning( P = 0. 149,P = 0. 095, respectively). Ramulus Cinnamomi and Radix Glycyrrhizae had significant two-way interaction (P = 0. 017 ). Conclusion : Ramulus Cinnamomi is the significant effect factor on the the contents of Asp, but the effect of Semen Armeniacae and Radix Glycynbizae is not significant.
出处 《中药药理与临床》 CAS CSCD 北大核心 2006年第1期1-2,共2页 Pharmacology and Clinics of Chinese Materia Medica
关键词 麻黄汤 配伍 天冬氨酸 Mahuang Tang( 麻黄汤 ) compatibility aspartic acid
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  • 1杨丽莉,屠锡德.气相色谱—质谱法测定血中伪麻黄碱[J].药学学报,1993,28(9):709-713. 被引量:34
  • 2[1]Li J L, Chen F L, Liu C M, et al. Determination of ephedrine and pseudoephedrine in MAHUANG TANG by GC-MS and effect of compatible medicinal herbs on concentration of components in decoction[J].Chin Tradit Herb Drugs(中草药),2002,33(4):307-309.
  • 3Bowyer J F, Hopkins K J, Jakab R, et al. L-Ephedrine-induced neurodegeneration in the parietal cortex and thalamus of the rat is dependent on hyperthermia and can be altered by the process of in vivo brain microdialysis [J]. Toxicol Lett,2001, 125(1-3): 156-166.
  • 4Paul J W, Dennis K M, Christina L L, et al. Effect of (-)-ephedrine on locomotion, feeding, and nucleus accumbens dopamine in rats [J]. Psychopharmocology, 1998, 135: 133-140.
  • 5Richard B W, Lawrence D F, Lance M W, et al. The effect on ephedrine prodrugs on locomotor activity in rats [J]. Gen Pharmac, 1996, 27(1): 109-111.
  • 6Dennis K M, Jack R N, Paul J W. Sensitization of anorexia and locomotion induced by chronic administration of ephedrine in rats [J]. Life Sci, 1999, 65(5): 501-511.
  • 7王平,刘玲,张六通,邱幸凡,石学敏.加味温胆汤对SAM-P/10老化痴呆鼠三个脑区递质氨基酸的影响[J].中国实验方剂学杂志,2001,7(4):24-27. 被引量:17
  • 8魏凤环,罗佳波,陈飞龙,贺丰.GC-MS法测定麻黄汤不同配伍对桂皮醛含量的影响[J].中草药,2004,35(6):635-638. 被引量:15

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