320例老年患者冠状动脉造影及其影响因素的研究

Clinic research about results of coronary arteriography and influencing factors in 320 aged patients

目的:探讨冠状动脉病变与临床多种因素的关系。方法:2002年1月至2004年10月的320例冠状动脉造影的病人,在多个投射角度作选择性左、右冠状动脉及左室造影,并以冠状动脉有无病变分为阳性组与阴性组,所有病人入院后均查血浆同型半胱氨酸(Hcy)、C-反应蛋白(CRP)、血尿酸(UA)水平。结果:冠脉造影阳性率占52．6％ (168／320),累及237支冠状动脉,其中左前降支占38．82％(92／237),回旋支占26．16％(62／237),左主干占6．33％ (15／237);右冠状动脉占28．69％(68／237)。与冠脉造影阴性组比较,阳性组患者血浆Hcy、CRP、UA水平显著升高(P<0．01)。结论:血浆Hcy、CRP、UA水平升高可能是冠心病的独立危险因素。

Objective： To explore the relation between coronary artery lesion and clinic influencing factor in 320 aged patients. Methods ： A total of 320 aged patients undergoing coronary angiography （CAG） were divided into two groups according to the results （positive or negative） of coronary arteriography. Plasma homocysteine （Hcy）, C reactive protein （CRP） and serum uric acid （UA） were measured in all patients. Results： The CAG positive rate was 52.6% （168/320） with 237 vessels involved. Among them positive rate of LAD was 38.82% （92/237）, LCX 26.16% （62/ 237）, LM （left main coronary artery） 6.33% （15/237）; RCA was 28.69% （68/237）. The plasma Hey. CRP and serum UA levels were significantly higher in the coronary artery disease （CAD） patients than those in controls （P〈 0.01）. Conclusion： The levels of blood Hey, CRP, or UA increase may be a risk factor of CAD.